Name of supervisor： Naoyuki Takemura,Doctorate (veterinary medicine)
Position: Professor
researchmap
KAKEN researcher number: 50227055
ORCID ID：0000-0002-4571-2701
Main research theme: Research on the mechanisms of occurrence, aggravation, and treatment of heart disease and kidney disease in dogs and cats.
Research keywords: small animals, heart failure, renal failure, pathophysiology
Lab location: Laboratory of Veterinary Internal Medicine Laboratory 2, 5th floor, Building D
E-mail：nstakemura(@mark)nvlu.ac.jp
Research
[Cardiology] We are analyzing the mechanisms of occurrence and deterioration of mitral regurgitation in dogs and hypertrophic cardiomyopathy in cats. At the same time, we are also considering treatment methods, including dietary therapy, for these two types of diseases. In addition, we are also conducting analysis and investigation of treatment methods for various arrhythmias that occur in connection with these diseases.
[Nephrology] We aim to establish an effective and less invasive hemodialysis protocol. In addition to analyzing the mechanisms of development and aggravation of chronic kidney disease in dogs and cats, we are also investigating treatments for these diseases.
Guidance policy for graduate students
Instructional policy
Basically, research themes are assigned to cardiology or nephrology according to the wishes of graduate students, and the themes are determined while discussing the content of previous research at multiple institutions and in our laboratory. Since it is a clinical laboratory, clinical research is the main focus. Research methods have been to create model animals and use them to conduct drug administration tests or retrospective or prospective clinical trials using samples and various data obtained from clinical cases.
Publications
1. Ogawa M, Kojima Y, Ishizaka M, Miyakawa H, Hsu HH, Miyagawa Y, Takemura N.
Plasma N-terminal pro-atrial natriuretic peptide concentrations are affected by dehydration in healthy dogs.
Open Vet J. 2023 May;13(5):604-612.
doi: 10.5455/OVJ.2023.v13.i5.13. Epub 2023 May 14. PMID: 37304609
2. Ogawa M, Nohara H, Hsu HH, Ishizaka M, Miyagawa Y, Takemura N.
Association between glomerular filtration rate and plasma N-terminal pro-atrial natriuretic peptide concentration in dogs.
Small Anim Pract. 2023 Sep;64(9):568-573.
doi: 10.1111/jsap.13626. Epub 2023 Jun 22. PMID: 37345758
3. Miyakawa H, Hsu HH, Ogawa M, Akabane R, Miyagawa Y, Takemura N.
Association between serum fibroblast growth factor-23 concentrations and blood calcium levels in chronic kidney disease cats with upper urolithiasis.
J Feline Med Surg. 2022 Dec;24(12):1245-1252.
doi:10.1177/1098612X221075278. Epub 2022 Feb 8. PMID: 35133180
4. Miyakawa H, Ogawa M, Sakatani A, Akabane R, Miyagawa Y, Takemura N.
Evaluation of the progression of non-azotemic proteinuric chronic kidney disease in dogs.
Res Vet Sci. 2021 Sep;138:11-18.
doi: 10.1016/j.rvsc.2021.05.018. Epub 2021 May 24. PMID: 34090202
