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Molecular Genetics

Toshinori OMI, MD, PhD

(Supervise Master and Doctoral Students)
Position : Professor
KAKEN researcher number : 40296091
Research keywords
Molecular Genetics, Blood Group, DNA Identification, Human, Companion Animal
Lab. Location : Department of Basic Science
4th Floor, Building E
E-mail : t.omi(@mark)nvlu.ac.jp

Guidance Policy for Graduate Students

 Our research foucus is to “search for genetic information useful for medical care and welfare.”

 My major research interest includes applied animal and human genetics in transfusion medicine, DNA identification technology, and biological diversity. Currently, my research focuses on animal genetics, in particular, the following:

1) Genetic variation of mitochondorial DNA hypervariable region 1 haplotype and short tandem repeat (STR) polymorphisms in dogs
2)Blood typing and candidate gene approach associated with erythrocyte antigens in dogs and cats
3)Identification of DNA markers associated with guide dog suitability

Guidance Policy for Graduate Students

 In the Master’s Program, students aim to acquire a wide range of knowledge and skills related to research. Students acquire various genetic and statistical analysis, etc. In the doctoral program, students sill conduct research on deeper themes and aim to become independent researchers. In addition, we provide thorough training in research ethics, academic presentations, and writing academic papers.

Note

It is desirable to have experience in basic genetic analysis such as PCR.
If you are interested in researching in this field, please contact us.

Publications

1. Iwamoto S, Omi T et.al. (1995). (Second author, Omi T)
Genomic organization of the glycoprotein D gene: Duffy blood group Fya/Fyb alloantigen system is associated with a polymorphism at the 44-amino acid residue.
Blood, 85(3), 622-6.
2. Omi T, Okuda H, et.al. (2000). (First and corresponding author, Omi T)
Detection of Rh23 in the partial D phenotype associated with the D(Va) category.
Transfusion, 40(2), 256-8
DOI: 10.1046/j.1537-2995.2000.40020256.x
3. Omi T, Kumada M, et.al. (2006). (First author, Omi T)
An intronic variable number of tandem repeat polymorphisms of the cold-induced autoinflammatory syndrome 1 (CIAS1) gene modifies gene expression and is associated with essential hypertension.
Eur J Hum Genet, 14(12), 1295-305.
DOI: 10.1038/sj.ejhg.5201698
4. Omi T, Nakazawa S, et.al. (2016).
(Master’s student co-first author, corresponding author, Omi T)
Molecular Characterization of the Cytidine Monophosphate-N-Acetylneuraminic Acid Hydroxylase (CMAH) Gene Associated with the Feline AB Blood Group System
PLoS One, 11(10):e0165000
DOI: 10.1371/journal.pone.0165000
5. Uno Y, Kawakami S, et.al. (2019).
(First author, doctoral student; corresponding author, Omi T)
Molecular characterization of cytidine monophospho-N-acetylneuraminic acid hydroxylase (CMAH) associated with the erythrocyte antigens in dogs.
Epidemiology Canine Genet Epidemiol, 7:6:9.
DOI: 10.1186/s40575-019-0076-1
6. Uno Y, Yaguchi M, et.al. (2021).
(First author, doctoral student; corresponding author, Omi T)
Phenotypic and Genetic Characterization for Incompatible Cross-Match Cases in the Feline AB Blood Group System.
Front Vet Sci, 13:8:720445
DOI: 10.3389/fvets.2021.720445
7. Kunita F, Udagwa C, et.al.(2024).
(First author, master’s student; corresponding author, Omi T)
Population genetics for 18 short tandem repeat loci (Canine GenotypesTM Panel 2.1 Kit) of 150 unrelated dogs from three pure-bred groups in Japan.
Legal Medicine, 70:102472
DOI: 10.1016/j.legalmed.2024.102472
Detailed Information (Researchmap)